Keratoacanthoma

Pronunciation

Definition 1

A rapidly growing, dome-shaped skin tumor that usually occurs on sun-exposed areas of the body, especially around the head and neck. Keratoacanthoma occurs more often in males. Although in most patients it goes away on its own, in a few patients it comes back. Rarely, it may spread to other parts of the body. (NCI Dictionary)

Definition 2

A dome-shaped, rapidly growing skin lesion composed of well differentiated squamous cells. It represents a proliferation of the infundibular epithelium of the hair follicle and its morphologic distinction from a well differentiated carcinoma may be difficult or impossible. Keratoacanthomas affect males more frequently than females and the majority tend to regress spontaneously. It has been suggested that keratoacanthoma represents a distinct subtype of squamous cell carcinoma of the skin. (NCI Thesaurus)

Definition 3

An epithelial skin neoplasm, composed of squamous cells, for which the malignancy status has not been established. (NCI Thesaurus/CDISC)

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