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KREBS CYCLE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
In all plants and animals: a series of enzymatic reactions in mitochondria involving oxidative metabolism of acetyl compounds to produce high-energy phosphate compounds that are the source of cellular energy
Synonyms:
citric acid cycle; Krebs citric acid cycle; Krebs cycle; tricarboxylic acid cycle
Classified under:
Nouns denoting natural processes
Hypernyms ("Krebs cycle" is a kind of...):
biological process; organic process (a process occurring in living organisms)
Meronyms (parts of "Krebs cycle"):
oxidative phosphorylation (an enzymatic process in cell metabolism that synthesizes ATP from ADP)
Holonyms ("Krebs cycle" is a part of...):
metabolic process; metabolism (the organic processes (in a cell or organism) that are necessary for life)
Context examples:
If oxygen is absent, electron transport and the Krebs cycle rapidly halt, leaving glycolysis and fermentation as the main means of energy production.
(Electron Transport Pathway, NCI Thesaurus/BIOCARTA)
The transfer of the amino group from aspartate to alpha-ketobutyrate creates oxaloacetate, a Krebs cycle intermediate.
(Feeding Amino Groups into the Urea Cycle, NCI Thesaurus/BIOCARTA)
These carriers produced in the Krebs cycle, along with those produced directly in beta-oxidation, transfer their energy to the electron transport chain where they drive the creation of the proton gradient that supports mitochondrial ATP production.
(Beta-Oxidation of Fatty Acids Pathway, NCI Thesaurus/BIOCARTA)
During aerobic exercise, the rapid consumption of ATP leads to use of the proton gradient to make more ATP, increased electron transport to regenerate the proton gradient, increased oxygen consumption, and increased activity of the Krebs cycle and glycolysis to supply high energy electrons to drive electron transport.
(Electron Transport Pathway, NCI Thesaurus/BIOCARTA)
