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LACKING
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Inadequate in amount or degree
Example:
tested and found wanting
Synonyms:
Classified under:
Similar:
inadequate; unequal (lacking the requisite qualities or resources to meet a task)
Sense 2
Meaning:
Nonexistent
Example:
her appetite was lacking
Synonyms:
absent; lacking; missing; wanting
Classified under:
Similar:
nonexistent (not having existence or being or actuality)
II. (verb)
Sense 1
-ing form of the verb lack
Context examples:
Mice lacking the c-Fos gene have overly dense bone and decreased bone resorption due to reduced osteoclast differentiation, indicating that c-Fos is an important mediator of osteoclast differentiation.
(Bone Remodeling Pathway, NCI Thesaurus/BIOCARTA)
These pathways are independent since the EndoG pathway still occurs in cells lacking DFF.
(Apoptotic DNA Fragmentation Pathway, NCI Thesaurus/BIOCARTA)
A single-chain immunotoxin consisting of Fv fragments of the BR96 monoclonal antibody (MoAb) and a truncated Pseudomonas exotoxin (PE40) that lacking the binding domain.
(BR96 sFv-PE40, NCI Thesaurus)
People lacking C1 inhibitor have also been identified and found to be prone to uncontrolled complement activation and dangerous swelling through production of C3a and C5a anaphylatoxins.
(Complement Pathway, NCI Thesaurus/BIOCARTA)
The eosinophil response in inflammation is absent in mice lacking CCR3, indicating the key role of this G protein coupled receptor in inflammation and allergic responses.
(CCR3 Signaling Pathway, NCI Thesaurus/BIOCARTA)
To better understand the roles of these related proteins in brain function using animal models, Shen and her colleagues created mice lacking both LRRK1 and LRRK2.
(Scientists find a role for Parkinson’s gene in the brain, The Titi Tudorancea Bulletin)
They also found that flies lacking the Arc gene form fewer connections between their motor neurons.
(Memory gene goes viral, National Institutes of Health)
We found that this zone lacking blood vessels was significantly enlarged in people with preclinical Alzheimer's disease.
(Predicting Alzheimer's Disease May Be Possible Using Eye Exam, The Titi Tudorancea Bulletin)
Neuropsychiatric Inventory (NPI) Is the patient less affectionate or lacking in emotions when compared to his/her usual self?
(NPI - Less Affectionate or Lacking in Emotions, NCI Thesaurus)
Metastasis is characteristic of advanced malignancies, but in rare instances can be seen in neoplasms lacking malignant morphology.
(Metastatic Neoplasm, NCI Thesaurus)
