Level of Evidence V

Opinion of respected authorities based on clinical experience, descriptive studies, or reports of expert committees. (NCI Thesaurus)

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Level of Evidence IV

Opinions of respected authorities based on clinical experience, consensus statements from expert committees, or authoritative reviews.

Level of Evidence III

Level of Evidence II

Prospective, nonrandomized, controlled trials; prospective cohort studies; prospective case series; and cross-sectional studies.

Level of Evidence I

Prospective, randomized, controlled trials and meta-analyses of prospective, randomized, controlled trials.

Level of Evidence 1A

Randomized, controlled clinical trial with total mortality as an endpoint.

Level of Evidence

A formal ranking system of the strength of evidence linked to a reported result.