Library / English Dictionary

    LEWIS

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    English critic and novelist; author of theological works and of books for children (1898-1963)play

    Synonyms:

    C. S. Lewis; Clive Staples Lewis; Lewis

    Classified under:

    Nouns denoting people

    Instance hypernyms:

    author; writer (writes (books or stories or articles or the like) professionally (for pay))

    Sense 2

    Meaning:

    United States novelist who satirized middle-class America in his novel Main Street (1885-1951)play

    Synonyms:

    Harry Sinclair Lewis; Lewis; Sinclair Lewis

    Classified under:

    Nouns denoting people

    Instance hypernyms:

    author; writer (writes (books or stories or articles or the like) professionally (for pay))

    Sense 3

    Meaning:

    United States labor leader who was president of the United Mine Workers of America from 1920 to 1960 and president of the Congress of Industrial Organizations from 1935 to 1940 (1880-1969)play

    Synonyms:

    John L. Lewis; John Llewelly Lewis; Lewis

    Classified under:

    Nouns denoting people

    Instance hypernyms:

    labor leader (a leader of a labor movement)

    Sense 4

    Meaning:

    United States explorer and soldier who lead led an expedition from St. Louis to the mouth of the Columbia River (1774-1809)play

    Synonyms:

    Lewis; Meriwether Lewis

    Classified under:

    Nouns denoting people

    Instance hypernyms:

    adventurer; explorer (someone who travels into little known regions (especially for some scientific purpose))

    Sense 5

    Meaning:

    United States athlete who won gold medals at the Olympics for his skill in sprinting and jumping (born in 1961)play

    Synonyms:

    Carl Lewis; Frederick Carleton Lewis; Lewis

    Classified under:

    Nouns denoting people

    Instance hypernyms:

    jumper (an athlete who competes at jumping)

    sprinter (someone who runs a short distance at top speed)

    Sense 6

    Meaning:

    United States rock star singer and pianist (born in 1935)play

    Synonyms:

    Jerry Lee Lewis; Lewis

    Classified under:

    Nouns denoting people

    Instance hypernyms:

    pianist; piano player (a person who plays the piano)

    rock star (a famous singer of rock music)

    Credits

     Context examples: 

    Cell surface carbohydrate molecules of the Lewis Y or Lewis X type that are detectable with monoclonal antibody B3.

    (B3 Antigen, NCI Thesaurus)

    It was not thought necessary in Sir Lewis de Bourgh's family.

    (Pride and Prejudice, by Jane Austen)

    It is being studied in the treatment of several types of cancer that express the Lewis Y antigen.

    (B3 monoclonal antibody, NCI Dictionary)

    MoAb BR96 specifically binds to Lewis Y-related carbohydrate antigen, a cell surface antigen overexpressed in many carcinomas.

    (BR96 sFv-PE40, NCI Thesaurus)

    Lewis Y Antigen Binding involves non-covalent interaction of a molecule through intermolecular physical forces of attraction with the Lewis Y cell surface antigen.

    (Lewis Y Antigen Binding, NCI Thesaurus)

    A murine IgG1 monoclonal antibody directed against Lewis Y antigen and related carbohydrate antigens of cell surface glycoproteins found in many tumor cells.

    (Monoclonal Antibody B3, NCI Thesaurus)

    Derived from Wistar stock by the laboratory of Dr. Lewis at the Wistar Institute in the 1940s and 1950s, the Lewis is a white albino rat with genotype a, TyrC.

    (Lewis, Rat Strain, NCI Thesaurus)

    A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A DTPA).

    (MOAB B-3-CHX-A-DTPA, NCI Thesaurus)

    An inherited disease affecting the metabolism of fucose, which affects the expression of the sialyl Lewis X antigen, the fucose-containing ligand for E- and P-selectins, resulting in a deficiency in neutrophil adhesion.

    (Leukocyte Adhesion Deficiency Type 2, NCI Thesaurus)

    The famous Lewis chessmen are made of walrus tusk.

    (Over-hunting walruses contributed to the collapse of Norse Greenland, University of Cambridge)


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