Health / Medical Topics

    Ligand-Independent Chloride Ion Channel Activation

    A process that involves the detection of and alteration of either the voltage or pH across a membrane, and results in a chloride channel becoming permeable to Cl- and related ions, including HCO3-, I-, SCN- and NO3-. This interaction plays a crucial role in setting the potential of the resting membrane, but also functions to regulate pH, the transport of organic solutes and the migration, differentiation and proliferation of cells. (NCI Thesaurus)




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