Health / Medical Topics

    Liquid Chromatography Mass Spectrometry

    Definition 1

    LC/MS is a hyphenated technique, combining the separation power of liquid chromatography (LC), an analytical chromatographic technique for separating ions or molecules dissolved in a solvent, with the detection power of mass spectrometry(MS), a technique to separate gas phase ions according their m/z (mass to charge ratio) value. Used for drug screening, pharmacology studies, environmental analyses and forensics. (NCI Thesaurus)

    Definition 2

    An analytical technique wherein liquid chromatography is coupled to mass spectrometry in order to separate, identify, and quantify substances in a sample. (NCI Thesaurus/CDISC)




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