Losartan potassium

Pronunciation

Definition 1

A drug used to treat high blood pressure. Losartan potassium blocks the action of chemicals that make blood vessels constrict (get narrower). It is a type of angiotensin II receptor antagonist. Also called Cozaar and losartan. (NCI Dictionary)

Definition 2

The potassium salt of losartan, a non-peptide angiotensin II receptor antagonist with antihypertensive activity. Losartan selectively and competitively binds to the angiotensin II receptor (type AT1) and blocks the binding of angiotensin II to the receptor, thus promoting vasodilatation and counteracting the effects of aldosterone. Converted from angiotensin I by angiotensin-converting enzyme (ACE), angiotensin II stimulates the adrenal cortex to synthesize and secrete aldosterone, decreasing sodium excretion and increasing potassium excretion, and acts as a vasoconstrictor in vascular smooth muscle. (NCI Thesaurus)

YOU MAY ALSO LIKE

Losartan

A drug used to treat high blood pressure. Losartan blocks the action of chemicals that make blood vessels constrict (get narrower). It…

Los Angeles Classification System

A classification system for the endoscopic assessment of reflux esophagitis based on the number and extent of mucosal breaks and their relationships…

Lorvotuzumab Mertansine

An immunoconjugate of a humanized murine monoclonal antibody (huN-901) and DMI, a semi-synthetic derivative of the plant-derived ansa macrolide maytansine. The antibody…

Loricrin

Loricrin (312 aa, 26 kDa) is encoded by the human LOR gene. This protein plays a role in the cell envelope structure…

Lordotic Position

Positioned with the patient leaning backward.

Lordosis

Abnormally increased curvature of the lumbar portion of the spinal column.