Library / English Dictionary

LOW-DENSITY LIPOPROTEIN

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A lipoprotein that transports cholesterol in the blood; composed of moderate amount of protein and a large amount of cholesterol; high levels are thought to be associated with increased risk of coronary heart disease and atherosclerosis

Synonyms:

beta-lipoprotein; LDL; low-density lipoprotein

Classified under:

Nouns denoting substances

Hypernyms ("low-density lipoprotein" is a kind of...):

lipoprotein (a conjugated protein having a lipid component; the principal means for transporting lipids in the blood)

Meronyms (substance of "low-density lipoprotein"):

LDL cholesterol (the cholesterol in low-density lipoproteins; the 'bad' cholesterol; a high level in the blood is thought to be related to various pathogenic conditions)

Credits

 Context examples: 

This allele, which encodes low-density lipoprotein receptor-related protein 1B, is involved in both the metabolism of low density lipoproteins and receptor-mediated endocytosis.

(LRP1B wt Allele, NCI Thesaurus)

This allele, which encodes LDLR chaperone MESD protein, plays a role in the modulation of the folding of low-density lipoprotein receptor family proteins.

(MESDC2 wt Allele, NCI Thesaurus)

This protein is involved in the folding of low-density lipoprotein receptor family proteins.

(LDLR Chaperone MESD, NCI Thesaurus)

Low-density lipoprotein receptor-related protein 6 (1613 aa, ~180 kDa) is encoded by the human LRP6 gene.

(Low-Density Lipoprotein Receptor-Related Protein 6, NCI Thesaurus)

Low-density lipoprotein receptor-related protein 5 (1615 aa, ~179 kDa) is encoded by the human LRP5 gene.

(Low-Density Lipoprotein Receptor-Related Protein 5, NCI Thesaurus)

Low-density lipoprotein (LDL) is a plasma lipoprotein particle whose lipid component includes cholesterol and triglycerides and is commonly referred to as bad cholesterol due to its role promoting atherogenic heart disease.

(LDL Pathway, NCI Thesaurus/BIOCARTA)

A lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides.

(Dyslipidemia, NCI Thesaurus)

Dextrothyroxine stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route.

(Dextrothyroxine, NCI Thesaurus)

A study warned that women with low levels of low-density lipoprotein cholesterol, sometimes called "bad cholesterol," may face an increased risk of bleeding stroke.

(Low Levels of Bad Cholesterol Increase Stroke Risk, The Titi Tudorancea Bulletin)

For example, high levels of low-density lipoprotein (LDL) cholesterol are associated with a greater risk for heart disease.

(Rare mutations reduce heart disease risk, NIH)