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MAXIMAL
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
The greatest or most complete or best possible
Example:
maximum pressure
Synonyms:
maximal; maximum
Classified under:
Similar:
sublime; supreme (greatest or maximal in degree; extreme)
Antonym:
minimal (the least possible)
Context examples:
This is achieved by elevating the drug plasma concentration to levels sufficient to saturate the maximal secretion capacity of the tubular cells.
(Aminohippurate Sodium, NCI Thesaurus)
Failure to capture manifests as a high pacing threshold that results in either intermittent failure to capture at maximal programmed output or excessive battery drain leading to premature battery exhaustion.
(Failure of Cardiac Pacemaker to Capture, NCI Thesaurus)
The Resource implements methods that allow maximal retention of animals when an infectious agent is detected in a barrier room.
(Barrier Animal Facility Shared Resource, NCI Thesaurus)
A microbial susceptibility test result in which the growth of microorganisms may be inhibited when higher than normal dosages of an antimicrobial agent are used and maximal possible blood concentration of the antimicrobial agent is achieved.
(Antimicrobial Dose Dependent Susceptibility Result, NCI Thesaurus)
Receptor binding by triiodothyronine in combination with recruited coactivators results in maximal transcriptional activation after binding to TREs; in general, binding of thyroid hormone receptor alone to TREs leads to repression of gene transcription
(Liothyronine, NCI Thesaurus)
Expressed most in prophase through metaphase, during maximal microtubule assembly from centrosomes, by human TUBG1 Gene (Tubulin Family), ubiquitous and highly conserved 451-aa 51-kDa Gamma Tubulin 1 is a component of microtubule organizing centers such as spindle poles or pericentriolar microtubule-nucleating material of centrosomes that interacts with GCP2 and GCP3 and may be involved in minus-end nucleation of microtubule assembly.
(Gamma Tubulin 1, NCI Thesaurus)
Calcium/CaM binding alone produces maximal activity of CaMKII, whereas CaMKI and CaMKIV have an activation loop that requires phosphorylation of a threonine residue by CaMK kinase (CaMKK) for maximal activity.
(Calmodulin Pathway, NCI Thesaurus/BIOCARTA)
