| Health / Medical Topics |
MLLT11 wt Allele
Human MLLT11 wild-type allele is located in the vicinity of 1q21 and is approximately 11 kb in length. This allele, which encodes protein AF1q, plays a role in both depolarization of and release of cytochrome c by the mitochondrion. The gene is involved in a translocation t(1;11)(q21;q23) with the MLL gene that is associated with acute leukemia. (NCI Thesaurus)
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This gene is involved in mitochondrial functions.
A fusion protein encoded by the MLLT10/PICALM fusion gene. This protein is comprised of the N-terminal zinc finger domain of protein AF-10…
A fusion gene that results from a chromosomal translocation t(10;11)(p13;q14) which fuses the 5' end of the MLLT10 gene to the extreme…
A fusion gene that results from a complex chromosomal rearrangement invins(10;11)(p12;q23q12) which fuses the 5' end of the MLLT10 gene with the…
Human MLLT10 wild-type allele is located in the vicinity of 10p12 and is approximately 209 kb in length. This allele, which encodes…
This gene may be involved in transcriptional regulation.
