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MOIETY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
One of two basic subdivisions of a tribe
Classified under:
Nouns denoting groupings of people or objects
Hypernyms ("moiety" is a kind of...):
social group (people sharing some social relation)
Holonyms ("moiety" is a member of...):
folk; tribe (a social division of (usually preliterate) people)
Sense 2
Meaning:
One of two (approximately) equal parts
Synonyms:
mediety; moiety
Classified under:
Nouns denoting quantities and units of measure
Hypernyms ("moiety" is a kind of...):
half; one-half (one of two equal parts of a divisible whole)
Context examples:
The monoclonal antibody moiety of DMUC5754A selectively binds to MUC16.
(MUC16-targeted Antibody-Drug Conjugate DMUC5754A, NCI Thesaurus)
In tumor cells, the NO donating moiety may block the cell cycle in the G1 and G2 phases and may induce apoptosis through caspase-mediated mechanisms.
(Nitric oxide-releasing acetylsalicylic acid derivative, NCI Thesaurus)
Upon administration, the antibody moiety of PF-06263507 selectively binds to cells expressing the 5T4 oncofetal antigen.
(Anti-5T4 Antibody-Drug Conjugate PF-06263507, NCI Thesaurus)
An adenine nucleotide comprised of three phosphate groups esterified to the sugar moiety, found in all living cells.
(Adenosine triphosphate, NCI Thesaurus)
Upon infusion of oxaliplatin-encapsulated transferrin-conjugated NGPE liposomes, the transferrin moiety targets and binds to the Tf receptor, which is overexpressed on a variety of human cancer cells.
(Oxaliplatin-Encapsulated Transferrin-Conjugated N-glutaryl Phosphatidylethanolamine Liposome, NCI Thesaurus)
The biological activity of this agent is derived from its interferon alpha-2b protein moiety.
(Peginterferon alfa-2b, NCI Thesaurus)
The PEG moiety inhibits proteolytic breakdown and clearance of IFN-a2b, which prolongs its half-life, extends the duration of its therapeutic effects and allows less frequent dosing.
(PEG-Proline-Interferon Alfa-2b, NCI Thesaurus)
The biological activity of this agent is derived from its interferon alpha-2a protein moiety.
(Peginterferon alfa-2a, NCI Thesaurus)
Following intravenous administration, aldoxorubicin binds selectively to the cysteine-34 position of albumin via its maleimide moiety.
(Aldoxorubicin, NCI Thesaurus)
The Ang2/VEGF peptide moieties of Ang2/VEGF-binding peptides-antibody fusion protein CVX-241 bind to Ang2 and VEGF receptors, which may inhibit tumor angiogenesis and tumor cell proliferation.
(Ang2/VEGF-Binding Peptides-Antibody Fusion Protein CVX-241, NCI Thesaurus)
