| Health / Medical Topics |
Monoclonal gammopathy of undetermined significance
Pronunciation
Definition 1
A benign condition in which there is a higher-than-normal level of a protein called M protein in the blood. Patients with monoclonal gammopathy of undetermined significance are at an increased risk of developing cancer. Also called MGUS. (NCI Dictionary)
Definition 2
A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Up to 25% of cases of monoclonal gammopathy of undetermined significance (MGUS) progress to a B-cell malignancy or myeloma. MGUS may occur in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases. (NCI Thesaurus)
YOU MAY ALSO LIKE
A laboratory test result indicating the presence of an abnormally high level of monoclonal immunoglobulins in the blood or urine.
A condition in which a higher-than-normal number of identical B cells are found in the blood. People with monoclonal B-cell lymphocytosis may…
Monoclonal antibodies used for clinical diagnosis
A monoclonal antibody (MOAB) directed against an antigen expressed by colorectal cancer cells.
A synthetic mouse monoclonal antibody which targets CD5+ lymphocytes. Monoclonal antibody T101 may be used in the immunotherapy of T-cell…
A murine monoclonal antibody (MoAb) with application in Immunotherapy and radioimmunodetection in T-cell malignancies. MoAb T101 recognizes a 65kD glycoprotein, CD5 antigen,…
