Health / Medical Topics

    Motesanib Diphosphate

    Definition 1

    The orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation. (NCI Thesaurus)

    Definition 2

    A substance that is being studied in the treatment of some types of cancer. It belongs to the families of drugs called angiogenesis inhibitors and protein kinase inhibitors. (NCI Dictionary)




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