MRE11A wt Allele

Human MRE11A wild-type allele is located in the vicinity of 11q21 and is approximately 77 kb in length. This allele, which encodes double-strand break repair protein MRE11A, is involved in the modulation of DNA recombination, telomere maintenance and double-strand break repair. Mutation of the gene is associated with ataxia telangiectasia-like disorder. (NCI Thesaurus)

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MRE11A Gene

This gene plays a role in DNA recombination and repair.

MRE11/RAD50 Double-Strand Break Repair Complex

The MRE11/RAD50 double-strand break repair complex consists of 5 proteins: Nibrin, p200, p400, MRE11, and RAD50. This complex possesses manganese-dependent single-stranded DNA…

MRC2 wt Allele

Human MRC2 wild-type allele is located in the vicinity of 17q23.2 and is approximately 66 kb in length. This allele, which encodes…

MRC2 Gene

This gene is involved in extracellular matrix remodeling.

MRC1 wt Allele

Human MRC1 wild-type allele is located in the vicinity of 10p12.33 and is approximately 102 kb in length. This allele, which encodes…

MRC1 Gene

This gene is involved in endocytosis of glycoproteins by macrophages.