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MU
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The 12th letter of the Greek alphabet
Classified under:
Nouns denoting communicative processes and contents
Hypernyms ("mu" is a kind of...):
alphabetic character; letter; letter of the alphabet (the conventional characters of the alphabet used to represent speech)
Holonyms ("mu" is a member of...):
Greek alphabet (the alphabet used by ancient Greeks)
Context examples:
Naltrexone reverses the effects of opioid analgesics by binding to the various opioid receptors in the central nervous system, including the mu-, kappa- and gamma-opioid receptors.
(Naltrexone, NCI Thesaurus)
As a chaperon, BiP binds to newly synthesized, unfolded mu immnoglobulin heavy chains prior to its assembly with light chains in the endoplasmic reticulum.
(OVA BiP Peptide, NCI Thesaurus)
Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors.
(Nalbuphine Hydrochloride, NCI Thesaurus)
A clonal disorder characterized by the secretion of a mu heavy chain that lacks a variable region.
(Mu Heavy Chain Disease, NCI Thesaurus)
Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions.
(Morphine, NCI Thesaurus)
Stimulation of the mu receptors produces the typical narcotic effects of analgesia, miosis, euphoria, respiratory depression, sedation, physical dependence and bradycardia.
(Dihydrocodeine Bitartrate, NCI Thesaurus)
Three types of heavy chain disease (HCD) have been recognized: gamma heavy chain disease (associated with Waldenstrom's macroglobulinemia), alpha heavy chain disease (also known as immunoproliferative small intestinal disease or Mediterranean lymphoma), and mu heavy chain disease (associated with chronic lymphocytic leukemia).
(Heavy Chain Disease, NCI Thesaurus)
The sulfonate moiety releases hydrogen sulfide (H2S), which is involved, through an as of yet not fully elucidated mechanism of action, in the modulation of visceral perception and pain, possibly through the activation of ATP-sensitive potassium (KATP) ion channels and mu opioid receptors.
(Opioid Agonist GIC-1001, NCI Thesaurus)
Functionally related to the poppy (Papaver somniferum) alkaloid morphine, natural or synthetic Opiates have widespread effects in the central nervous system, and on smooth muscle, due to activation of specific delta, mu, and kappa opiate receptors (each controlling different brain functions).
(Opiate, NCI Thesaurus)
Studies suggest that once activated, the mu receptor turns on 2 signaling pathways.
(Designing more effective opioids, NIH)
