| Health / Medical Topics |
MUC-1 Antigen
Definition 1
MUC-1 antigen is a mammary-type apomucin, a high molecular weight transmembrane glycoprotein, of which the extracellular domain is formed by a repeating 20 amino acid sequence (in tandem) with a high content of serine and threonine on which are O-linked carbohydrate chains. MUC-1 synthesis and secretion are features of glandular epithelial tissues; MUC-1 is overexpressed in lactating breast and in breast, ovary, lung, and prostate malignancies. (NCI Thesaurus)
Definition 2
A substance found on certain epithelial cells (cells that cover organs, glands, and other body surfaces) and on breast cells involved in making milk. It is also found on tumors of the breast, ovary, lung, and prostate. MUC-1 is a type of tumor marker. (NCI Dictionary)
YOU MAY ALSO LIKE
A protein found on certain epithelial cells, which line the inside and outside surfaces of the body. It may be found in…
A clonal disorder characterized by the secretion of a mu heavy chain that lacks a variable region. Most patients present with…
The determination of the ratio of mu glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a…
The determination of the amount of mu glutathione-s-transferase present in a sample.
A drug used to treat some types of cancer, rheumatoid arthritis, and severe skin conditions, such as psoriasis. MTX stops cells from…
Human MTRR wild-type allele is located in the vicinity of 5p15.31 and is approximately 55 kb in length. This allele, which encodes…
