Multiple Transversion Abnormalities

Multiple point mutations in a DNA sequence from eukaryotic or prokaryotic organisms in which each mutation occurs by substitution of a purine base for a pyrimidine base or vice versa. These abnormalities can be either heritable or occur somatically. (NCI Thesaurus)

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A rare neurodegenerative disorder characterized by loss of autonomic nervous system functions and disturbances of motor, balance and muscle coordination.

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