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MYELOBLAST
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A precursor of leukocytes that normally occurs only in bone marrow
Classified under:
Hypernyms ("myeloblast" is a kind of...):
leucocyte; leukocyte; WBC; white blood cell; white blood corpuscle; white cell; white corpuscle (blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system)
Context examples:
When the proliferating cells are immature myeloid cells and myeloblasts, it is called acute myeloid leukemia.
(Myeloid Leukemia, NCI Thesaurus)
The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia.
(Myelodysplastic syndrome, NCI Thesaurus/WHO)
Myeloblasts become mature white blood cells called granulocytes (neutrophils, basophils, and eosinophils).
(Myeloblast, NCI Dictionary)
The bone marrow and the peripheral blood show large myeloblasts with abundant basophilic cytoplasm, often containing azurophilic granules.
(Acute Myeloid Leukemia with t(8;21)(q22;q22); RUNX1-RUNX1T1, NCI Thesaurus/WHO)
An aggressive (fast-growing) disease in which too many myeloblasts (immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood.
(Acute myeloblastic leukemia, NCI Dictionary)
A granulocytic sarcoma composed primarily of myeloblasts (WHO 2001).
(Blastic Granulocytic Sarcoma, NCI Thesaurus)
Acute erythroid leukemia characterised by the presence of at least 50% erythroid precursors and at least 20% myeloblasts in the bone marrow. — 2003
(Erythroleukemia, NCI Thesaurus)
A granulocytic sarcoma composed of myeloblasts and promyelocytes (WHO 2001). —2003
(Immature Granulocytic Sarcoma, NCI Thesaurus)
The malignant cells show minimal differentiation and are called blasts, either myeloid blasts (myeloblasts) or lymphoid blasts (lymphoblasts).
(Acute leukemia, NCI Thesaurus)
Rod-shaped structures of uncertain nature in the cytoplasm of immature myeloid cells, especially myeloblasts, in acute myelocytic leukemia; may be an abnormal form of lysosomes; they contain peroxidase and acid phosphatase, and stain red by azure-eosin stains.
(Auer Rod, NCI Thesaurus)
