| Health / Medical Topics |
N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl) Urea
An orally available isoxazole urea with potential anti-tumor activity. In preclinical trials, N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl)urea inhibited raf kinase, an enzyme capable of reversing the phenotype of ras-transformed cells and blocking tumor growth. (NCI Thesaurus)
YOU MAY ALSO LIKE
A phenylretinamide and synthetic retinoid analogue. N-(4-methoxyphenyl)retinamide (4-MPR) may activate retinoic acid receptors, thereby altering the expression of certain genes leading to…
A phenylretinamide and synthetic retinoid analogue. N-(4-hydroxyphenyl)-9-cis-retinamide may activate retinoic acid receptors, thereby altering the expression of certain genes leading to cell…
A phenylretinamide and synthetic retinoid analogue. N-(4-ethoxyphenyl)retinamide may bind to and activate retinoic acid receptors (RARs), thereby inducing changes in the expression…
A thiocarboxanilide non-nucleoside reverse transcriptase inhibitor. UC-781 is a potent inhibitor of reverse transcriptase-dependent pyrophosphorolysis, and purportedly restores the chain-terminating activity of…
A phenylretinamide and synthetic retinoid analogue. N-(2-carboxyphenyl)retinamide may bind to and activate retinoic acid receptors (RARs), thereby inducing changes in the expression…
One criteria of the TNM staging system. N refers to the extent of lymph node involvement.
