Health / Medical Topics

    Nidogen-2

    Nidogen-2 (1375 aa, ~151 kDa) is encoded by the human NID2 gene. This protein plays a role in both basement membrane structure and cell adhesion. (NCI Thesaurus)




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    The 20 kDa C-terminal domain of the vascular basement protein, Nidogen-1. It may have anti-angiogenic properties.
    Nidogen, a 150-kD sulfated glycoprotein, is a major component of basement membranes and forms a highly stable noncovalent complex with laminin. …
    Human NID2 wild-type allele is located in the vicinity of 14q22.1 and is approximately 64 kb in length. This allele, which encodes…
    This gene plays a structural role in the basement membrane.
    Human NID1 wild-type allele is located in the vicinity of 1q43 and is approximately 98 kb in length. This allele, which encodes…
    This gene plays a role in the compositional regulation of basement membranes and has anti-angiogenic activity.

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