| Health / Medical Topics |
Nitric Oxide Synthase 2C
Encoded by human NOS2C Gene (NOS Family), calcium/calmodulin stimulated homodimeric Nitric Oxide Synthase 2C binds FAD and FMN cofactors, requires BH4 which may stabilize the dimer, and synthesizes reactive free radical nitric oxide messenger (from L-arginine). NO has antimicrobial and antitumoral activities in macrophages. NOS2C may bind SLC9A3R1. IL12 requires NOS2 to stimulate NK cell cytotoxicity and to activate STAT4 tyrosine-phosphorylation by TYK2 in innate immunity. (NCI Thesaurus)
YOU MAY ALSO LIKE
Encoded by human NOS2B Gene (NOS Family), calcium/calmodulin stimulated homodimeric Nitric Oxide Synthase 2B binds FAD and FMN cofactors, requires BH4 which…
Glutamatergic-mediated nitric oxide (NO) production occurs via the N-methyl-D-aspartic acid (NMDA) postsynaptic density protein 95 (PSD95)-neuronal nitric oxide synthase (NOS1) ternary…
Nitric oxide (NO) has a number of important physiological actions in the cardiovascular system. In the heart, NO plays a role…
The determination of the amount of nitric oxide present in a sample.
An unstable free-radical gas which reacts rapidly with oxygen to form nitrogen oxides. Water soluble, NO is produced normally in numerous…
A toxic, corrosive, colorless liquid used to make fertilizers, dyes, explosives, and other chemicals.
