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NOREPINEPHRINE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A catecholamine precursor of epinephrine that is secreted by the adrenal medulla and also released at synapses
Synonyms:
Classified under:
Hypernyms ("norepinephrine" is a kind of...):
pressor; vasoconstrictive; vasoconstrictor (any agent that causes a narrowing of an opening of a blood vessel: cold or stress or nicotine or epinephrine or norepinephrine or angiotensin or vasopressin or certain drugs; maintains or increases blood pressure)
monoamine neurotransmitter (a monoamine that is functionally important in neural transmission)
catecholamine (any of a group of chemicals including epinephrine and norepinephrine that are produced in the medulla of the adrenal gland)
Context examples:
Most paraganglia secrete epinephrine and norepinephrine.
(Paraganglia, NCI Dictionary)
Pamelor increases the levels of norepinephrine and other natural chemicals in the brain.
(Pamelor, NCI Dictionary)
The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity.
(Atomoxetine Hydrochloride, NCI Thesaurus)
A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors).
(Clozapine, NCI Thesaurus)
These agents block the action of natural sympathomimetic neurotransmitters (norepinephrine and related substances), and can initiate physiological responses such as vasodilation, bradycardia, and pupil contraction.
(Alpha-adrenergic antagonist, NCI Thesaurus)
Neurons in the locus coeruleus release both dopamine and another chemical called norepinephrine.
(How novelty boosts memory retention, NIH)
Further experiments showed that stimulation of the vagus nerve triggered the adrenal glands to release catecholamines, including dopamine and norepinephrine.
(Electroacupuncture Reduces Sepsis in Mice, NIH)
Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action.
(Norepinephrine Bitartrate, NCI Thesaurus)
A synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine.
(Norepinephrine, DL-, NCI Thesaurus)
Nadolol competitively blocks beta-1 adrenergic receptors located in the heart and vascular smooth muscle, inhibiting the activities of the catecholamines epinephrine and norepinephrine and producing negative inotropic and chronotropic effects.
(Nadolol, NCI Thesaurus)
