Health / Medical Topics

    Nucleoporin

    Definition 1

    Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The proteins encoded by these genes function in the nuclear transport of protein and RNA. (from LocusLink 4928, OMIM 601021) (NCI Thesaurus)

    Definition 2

    Proteins that form the structure of the nuclear pore. They are involved in active, facilitated and passive transport of molecules in and out of the cell nucleus. (NLM, Medical Subject Headings)




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