Library / English Dictionary

    OLIGOSACCHARIDE

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Any of the carbohydrates that yield only a few monosaccharide molecules on complete hydrolysisplay

    Classified under:

    Nouns denoting substances

    Hypernyms ("oligosaccharide" is a kind of...):

    carbohydrate; saccharide; sugar (an essential structural component of living cells and source of energy for animals; includes simple sugars with small molecules as well as macromolecular substances; are classified according to the number of monosaccharide groups they contain)

    Hyponyms (each of the following is a kind of "oligosaccharide"):

    disaccharide (any of a variety of carbohydrates that yield two monosaccharide molecules on complete hydrolysis)

    tetrasaccharide (any of a variety of carbohydrates that yield four monosaccharide molecules on complete hydrolysis)

    trisaccharide (any of a variety of carbohydrates that yield three monosaccharide molecules on complete hydrolysis)

    Credits

     Context examples: 

    Many complex O-linked oligosaccharides are presumably added by glycosyltransferases.

    (Mucin Peptide MUC-1, NCI Thesaurus)

    Class of oligosaccharides produced by plants that are polymers mainly comprised of fructose (generally 2 to 140) units usually with a glucose end.

    (Inulin, NCI Thesaurus/CRCH)

    Galactosyltransferase catalyzes the formation of a glycosidic bond between galactose and N-acetyl-D-glucosamine to create N-acetyllactosamine (D-galactosyl-N-acetyl-D-glucosamine), found in the oligosaccharides of glycoproteins.

    (Lactose Synthesis Pathway, NCI Thesaurus/BIOCARTA)

    GD2 is a glycosphingolipid (ceramide and oligosaccharide) that may be highly expressed by melanomas and other neuroectodermal tumors, while only minimally expressed by normal tissues.

    (Monoclonal Antibody 4B5 Anti-Idiotype Vaccine, NCI Thesaurus)

    An oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus.

    (Aclarubicin, NCI Thesaurus)

    Most of the proteins synthesized in the ER are cotranslationally modified with N (asparagine)-linked glycans by addition of triglycosylated, branched oligosaccharides at asparagines residues.

    (Endoplasmic Reticulum Degradation Pathway, NCI Thesaurus/BIOCARTA)

    This protein plays a role in the addition of high-mannose oligosaccharides to asparagine residues.

    (Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit DAD1, NCI Thesaurus)

    Phytohemagglutinin binds to complex oligosaccharides containing galactose, N-acetylglucosamine and mannose, causing agglutination of most mammalian red blood cell types.

    (Phytohemagglutinin, NCI Thesaurus)

    A glycosylation site is an amino acid residue within a peptide that accepts oligosaccharide via amide linkage, specifically through amide nitrogen of asparagine via N-acetylglucosamine, as one of the post-translational modifications.

    (N-Glycosylation Site, NCI Thesaurus)

    In addition, acarbose inhibits pancreatic alpha-amylase which hydrolyzes complex starches to oligosaccharides in the small intestines.

    (Acarbose, NCI Thesaurus)


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