Olivomycin

Definition 1

A mixture of several closely related glycosidic antibiotics, obtained from Actinomyces (or Streptomyces) olivoreticuli with antifungal and antineoplastic activities. Olivomycin inhibits mitochondrial H+-ATP synthase. They are used as fluorescent dyes that bind to DNA and prevent both RNA and protein synthesis. In addition, olivomycin antibiotics are able to induce apoptosis in tumor cells through a mechanism that has not been fully elucidated. (NCI Thesaurus)

Definition 2

A mixture of several closely related glycosidic antibiotics obtained from Actinomyces (or Streptomyces) olivoreticuli. They are used as fluorescent dyes that bind to DNA and prevent both RNA and protein synthesis and are also used as antineoplastic agents. (NLM, Medical Subject Headings)

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