Library / English Dictionary

    OVERACTIVE

    Pronunciation (US): Play  (GB): Play

     I. (adjective) 

    Sense 1

    Meaning:

    More active than normalplay

    Example:

    a hyperactive child

    Synonyms:

    hyperactive; overactive

    Classified under:

    Adjectives

    Similar:

    active (characterized by energetic activity)

    Derivation:

    overactivity (excessive activity)

    Credits

     Context examples: 

    In addition, METAP2 inhibition also down-regulates ERK1/2 signaling pathway, which is usually overactive in the fat tissues of obese people.

    (Beloranib, NCI Thesaurus)

    By contrast, they suggest overactive neurons could result in exaggerated simulation of what others might be thinking, which may play a role in social anxiety.

    (‘Mindreading’ neurons simulate decisions of social partners, University of Cambridge)

    The new finding suggests a critical role for an overactive orexin system in producing panic attacks.

    (The Mechanism of Panic Attacks, NIH, US)

    Post-traumatic stress disorder, or PTSD, is caused by an overactive fear memory and includes a broad range of psychological symptoms that can develop after someone goes through a traumatic event.

    (Antibiotics Could Prevent, Cure PTSD, The Titi Tudorancea Bulletin)

    Careful administration of very small doses of toxin can restrict its action locally to reduce overactive muscles, such as those involved in twitching of the eyes.

    (Botulin Pathway, NCI Thesaurus/BIOCARTA)

    In autoimmune diseases, white blood cells become overactive, and instead of attacking bacteria and viruses, the immune system assaults various tissues in the body.

    (Anti-inflammatory Drugs Also Fight Depression, Voanews)

    Also called overactive thyroid.

    (Hyperthyroidism, NCI Dictionary)

    HSP90 maintains the stability and functional shape of many oncogenic signaling proteins and the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be over-expressed or overactive in tumor cells.

    (Ansamycin Antineoplastic Antibiotic, NCI Thesaurus)

    You may have overactive bladder if you have two or more of these symptoms: • You urinate eight or more times a day or two or more times at night • You have the sudden, strong need to urinate immediately • You leak urine after a sudden, strong urge to urinate

    (Overactive Bladder, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)


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