Library / English Dictionary

    PATHWAY

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A trodden pathplay

    Synonyms:

    footpath; pathway

    Classified under:

    Nouns denoting man-made objects

    Hypernyms ("pathway" is a kind of...):

    path (a way especially designed for a particular use)

    Sense 2

    Meaning:

    A bundle of myelinated nerve fibers following a path through the brainplay

    Synonyms:

    nerve pathway; nerve tract; pathway; tract

    Classified under:

    Nouns denoting body parts

    Hypernyms ("pathway" is a kind of...):

    substantia alba; white matter (whitish nervous tissue of the CNS consisting of neurons and their myelin sheaths)

    Hyponyms (each of the following is a kind of "pathway"):

    optic radiation; radiatio optica (a nerve pathway from the lateral geniculate body to the visual cortex)

    commissure (a bundle of nerve fibers passing from one side to the other of the brain or spinal cord)

    cerebral peduncle; peduncle (a bundle of myelinated neurons joining different parts of the brain)

    Credits

     Context examples: 

    Agrin also engages signaling pathways of several potent oncogenes (i.e., SFK, ErbB receptors, and cortactin).

    (Agrin Pathway, NCI Thesaurus/BIOCARTA)

    Inactivating mutations of APC cause accumulation of beta-Catenin, which binds TCF4 and increases transcription of target genes (e.g., c-MYC) and binds GSK3-beta in the WNT signaling pathway.

    (Adenomatous Polyposis Coli Protein, NCI Thesaurus)

    XIAP interferes with both the intrinsic and extrinsic program-death signaling pathways, which may render tumor cells resistant to apoptosis.

    (AEG35156, NCI Thesaurus)

    There were pathways for animals and plants to move along.

    (Scientists return from expedition to lost continent of Zealandia, National Science Foundation)

    Then take this pathway on the left, I pray thee, and then the deer-track which passes on the right.

    (The White Company, by Sir Arthur Conan Doyle)

    More severe symptoms of psychosis were associated with higher NM-MRI signals in the nigrostriatal pathway of individuals with schizophrenia and in those at-risk for schizophrenia.

    (Neuromelanin-sensitive MRI identified as a potential biomarker for psychosis, National Institutes of Health)

    A solar eclipse is coming (all solar eclipses are new moons), and they are known to open a pathway, and because eclipses speed timetables, a professional breakthrough seems to be coming quickly.

    (AstrologyZone.com, by Susan Miller)

    We had come on a small black ribbon of pathway.

    (The Return of Sherlock Holmes, by Sir Arthur Conan Doyle)

    Afuresertib binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

    (Afuresertib, NCI Thesaurus)

    DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability.

    (Mismatch Repair Pathway, NCI Thesaurus/KEGG)


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