Patient Determined Disease Steps Questionnaire

Definition 1

A standardized rating scale developed by Hohol et al in 1995, which is a self-assessment scale of functional disability in multiple sclerosis patients primarily based on ambulation. The questionnaire contains 1 question which is scored ranging from 0 (normal) to 8 (bedridden). A score of 0 to 2 indicates mild disability; a score of 3 to 5 indicates moderate disability; a score of 6 to 8 indicates severe disability. (NCI Thesaurus)

Definition 2

Patient Determined Disease Steps (PDDS) (Hohol MJ, Orav EJ, Weiner HL. Disease Steps in multiple sclerosis: A simple approach to evaluate disease progression. Neurology 1995; 45: 251-55). (Hohol MJ, Orav EJ, Weiner HL. Disease Steps in multiple sclerosis: a longitudinal study comparing disease steps and EDSS to evaluate disease progression. Multiple Sclerosis 1999; 5: 349-54). (Marrie RA and Goldman M. Validity of performance scales for disability assessment in multiple sclerosis. Multiple Sclerosis 2007; 13: 1176-1182). (The PDDS and/or PS are provided for use by the NARCOMS Registry: www.narcoms.org/pdds. NARCOMS is supported in part by the Consortium of Multiple Sclerosis Centers (CMSC) and the CMSC Foundation). (NCI Thesaurus/CDISC)

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