Library / English Dictionary

PHOSPHOPROTEIN

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Containing chemically bound phosphoric acid

Classified under:

Nouns denoting substances

Hypernyms ("phosphoprotein" is a kind of...):

protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)

Hyponyms (each of the following is a kind of "phosphoprotein"):

casein (a milk protein used in making e.g. plastics and adhesives)

Credits

 Context examples: 

CD20 is a non-glycosylated cell surface phosphoprotein that is exclusively expressed on B cells during most stages of B cell development.

(Ocaratuzumab, NCI Thesaurus)

Phosducin, encoded by the PDC gene, is a phosphoprotein that is located in the outer and inner segments of the rod cells in the retina.

(Phosducin, NCI Thesaurus/LocusLink)

This protein plays a role in signaling and as both a dual-specificity phosphoprotein phosphatase and a lipid phosphatase.

(Phosphatidylinositol-3,4,5-Trisphosphate 3-Phosphatase and Dual-Specificity Protein Phosphatase PTEN, NCI Thesaurus)

Encoded by Protein Phosphatase Genes, Protein Phosphatase enzymes remove tyrosine-, serine-, or threonine-bound phosphate groups from many phosphoproteins, including enzymes phosphorylated by a tyrosine kinase or a serine/threonine kinase.

(Phosphoprotein Phosphatase, NCI Thesaurus)

This allele, which encodes astrocytic phosphoprotein PEA-15 protein, may be involved in the modulation of signaling, transport of carbohydrates and protein localization.

(PEA15 wt Allele, NCI Thesaurus)

STMN1, a ubiquitous cytosolic phosphoprotein and tubulin modulator that plays a key role in mitosis, is overexpressed in a variety of tumors and correlates with poor prognosis.

(pbi-shRNA STMN1 Lipoplex, NCI Thesaurus)

ETS1 encodes 42-52 kD nuclear phosphoprotein transcription factors that interact with purine-rich promoter/enhancer sequences in the TCRA gene.

(Oncogene ETS, NCI Thesaurus)

HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival.

(p53/HDM2 Interaction Inhibitor CGM097, NCI Thesaurus)

This allele, which encodes phosphoprotein associated with glycosphingolipid-enriched microdomains 1, is involved in T cell receptor signal transduction repression.

(PAG1 wt Allele, NCI Thesaurus)

This allele, which encodes carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, plays a role in the hydrolysis of phosphoproteins.

(CTDSP2 wt Allele, NCI Thesaurus)