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Pixantrone
Pronunciation
Definition 1
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antitumor antibiotics. Also called BBR 2778. (NCI Dictionary)
Definition 2
A synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. (NCI Thesaurus)
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