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PLASMA CELL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood
Synonyms:
Classified under:
Hypernyms ("plasma cell" is a kind of...):
lymph cell; lymphocyte (an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection)
Hyponyms (each of the following is a kind of "plasma cell"):
plasmablast (the precursor of a plasma cell)
Context examples:
MALT consists of a collection of predominantly small lymphocytes, fewer larger, transformed lymphocytes, and plasma cells.
(Mucosa-Associated Lymphoid Tissue, NCI Thesaurus)
This allele, which encodes B-lymphocyte antigen CD20 protein, plays a role in the development and differentiation of B-cells into plasma cells.
(MS4A1 wt Allele, NCI Thesaurus)
A small protein made by plasma cells (white blood cells that produce antibodies).
(Bence Jones protein, NCI Dictionary)
CD19 is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages.
(Anti-CD19 Monoclonal Antibody MDX-1342, NCI Thesaurus)
A protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the body to make a specific immune response).
(Antibody, NCI Dictionary)
In the plasma cell type there is pronounced plasma cell proliferation.
(Angiofollicular Lymphoid Hyperplasia, NCI Thesaurus)
Expression of BCL6 in some B-cells early in the antigen response may skew them toward a germinal center fate, away from a plasma cell fate.
(BCL6 Protein, NCI Thesaurus)
If the interaction between CD40 and CD40L is prolonged, the B cell can be induced to become a memory cell rather than a plasma cell.
(Antigen Dependent B Cell Activation Pathway, NCI Thesaurus/BIOCARTA)
CD19 is a membrane antigen that is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages.
(Anti-CD19 Monoclonal Antibody MEDI-551, NCI Thesaurus)
It is characterized by destructive infiltration of lymph nodes and extranodal sites by a monotonous population of transformed B-lymphocytes or plasma cells.
(Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder, NCI Thesaurus)
