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PLASMID
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication
Synonyms:
plasmid; plasmid DNA
Classified under:
Nouns denoting natural objects (not man-made)
Hypernyms ("plasmid" is a kind of...):
cellular inclusion; inclusion; inclusion body (any small intracellular body found within another (characteristic of certain diseases))
Context examples:
A synthetic peptide used to formulate and deliver deoxyribonucleic acids (DNA, usually in plasmid form) in gene therapy.
(DNA Compaction Peptide, NCI Thesaurus)
A murine retrovirus that contains plasmid DNA (cDNA) coding for the B chain of platelet-derived growth factor (PDGFB).
(Murine Retrovirus Containing Human PDGFB cDNA, NCI Thesaurus)
Hold a larger insert than plasmids or cosmids.
(P1-derived Artificial Chromosome, NCI Thesaurus)
A plasmid especially designed for cloning of DNA or construction of recombinant DNA molecules.
(Plasmid Cloning Vector, NCI Thesaurus)
A vaccine consisting of a plasmid DNA encoding the murine prostate-specific membrane antigen (PSMA).
(Mouse Prostate-Specific Membrane Antigen Plasmid DNA Vaccine, NCI Thesaurus)
A vaccine consisting of a plasmid DNA encoding the murine melanoma-associated antigen gp100.
(Mouse gp100 Plasmid DNA Vaccine, NCI Thesaurus)
They are or are derived from plasmids, bacteriophages, or viruses and are used for transporting foreign genes into recipient cells.
(Cloning Vector, NCI Thesaurus)
An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities.
(Allogeneic GM-CSF-secreting Tumor Vaccine PANC 10.05 pcDNA-1/GM-Neo, NCI Thesaurus)
Upon cell entry, activation of the H19 gene promoter-containing plasmids and DTA expression are limited to tumor cells, as high levels of H19 expression are only found in tumor cells.
(BC-819 Plasmid/Polyethylenimine Complex, NCI Thesaurus)
Temperate tailed phagae; does not integrate into host chromosome; prophage resembles plasmid and replicates autonomously at low numbers.
(Bacteriophage P1, NIH CRISP Thesaurus)
