Platelet Basic Protein

A product of the PPBP gene, pro-platelet basic protein is processed into platelet basic protein (PBP) and connective-tissue-activating peptide III (CTAP-III). Upon platelet activation these proteins undergo further processing into beta thromboglobulin (Beta-TG) and neutrophil-activating peptide 2 (NAP2), respectively. Many of the function ascribed to CTAP-III may actually be the result of processing to NAP-2. (NCI Thesaurus)

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