PLK3 wt Allele

Human PLK3 wild-type allele is located in the vicinity of 1p34.1 and is approximately 6 kb in length. This allele, which encodes serine/threonine-protein kinase PLK3 protein, plays a role in the regulation of M phase functions during the cell cycle. The PLK3 gene is down-regulated in certain types of cancer (head and neck squamous cell carcinomas, lung carcinomas) and overexpressed in other types of cancer (breast carcinomas and highly-proliferating malignant epithelial ovarian tumors). (NCI Thesaurus)

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PLK3 Gene

This gene is involved in the regulation of mitosis.

PLK2 wt Allele

Human PLK2 wild-type allele is located within 5q12.1-q13.2 and is approximately 6 kb in length. This allele, which encodes serine/threonine-protein kinase PLK2…

PLK2 Gene

This gene is involved in normal cell division.

PLK1 wt Allele

Human PLK1 wild-type allele is located in the vicinity of 16p12.1 and is approximately 11 kb in length. This allele, which encodes…

PLK1 Inhibitor TAK-960

An orally available, Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor TAK-960 selectively inhibits PLK1, inducing selective…

PLK1 Gene

This gene plays a role in mitotic regulation.