PM00104

A synthetic alkaloid compound, related to natural alkaloid compounds, found in molluscs (jorumycin) and sponges (renieramycins), with potential antineoplastic activity. PM00104 reversibly binds to DNA, thereby inducing cytotoxicity due to its interference with DNA replication, transcription, and translation processes. DNA binding by this agent does not trigger DNA damage checkpoint responses, hence PM00104 demonstrates a manageable and reversible cytotoxicity as part of its antitumor activity. (NCI Thesaurus)

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No morphologic evidence of distant metastasis, in accordance with TNM classification system guidelines.

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A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to…

pM-81

A monoclonal antibody that is being studied in the detection and treatment of cancer. Monoclonal antibodies are produced in the laboratory and…

PM Only Probe Correction Method

Make no adjustment to the perfect match (PM) probe levels. Defined in the documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html

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Human PLXDC1 wild-type allele is located in the vicinity of 17q21.1 and is approximately 90 kb in length. This allele, which encodes…

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This gene is involved in capillary formation.