Library / English Dictionary

    POLYMERIZATION

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A chemical process that combines several monomers to form a polymer or polymeric compoundplay

    Synonyms:

    polymerisation; polymerization

    Classified under:

    Nouns denoting natural processes

    Hypernyms ("polymerization" is a kind of...):

    chemical action; chemical change; chemical process ((chemistry) any process determined by the atomic and molecular composition and structure of the substances involved)

    Derivation:

    polymerize (undergo polymerization)

    polymerize (cause (a compound) to polymerize)

    Credits

     Context examples: 

    Unlike other tubulin inhibitors such as the taxanes and vinca alkaloids, noscapine does not affect microtubule polymerization.

    (Noscapine Hydrochloride, NCI Thesaurus)

    This protein is involved in the modulation of both actin polymerization and formation of branching actin structures.

    (Actin-Related Protein 2/3 Complex Subunit 1B, NCI Thesaurus)

    Wave-1 activation by Rac1 and Nck releases Wave-1 with Hspc300 to activate actin Y branching and polymerization by Arp2/3.

    (Actin Branching Pathway, NCI Thesaurus/BIOCARTA)

    An antimitotic agent that binds to tubulin and inhibits tubulin polymerization and arrests proliferation of tumor cells.

    (Allocolchicine, NCI Thesaurus)

    Batabulin covalently binds to beta tubulin, resulting in a disruption of microtubule polymerization, collapse of the cytoskeleton, cell cycle arrest, and tumor cell apoptosis.

    (Batabulin, NCI Thesaurus)

    After internalization of the drug conjugate and proteolytic cleavage of the linker, MMAE binds to tubulin and inhibits its polymerization, which results in G2/M-phase growth arrest and tumor cell apoptosis.

    (MUC16-targeted Antibody-Drug Conjugate DMUC5754A, NCI Thesaurus)

    MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in cell cycle arrest at the G2/M phase and apoptosis.

    (MKC-1, NCI Thesaurus)

    Microtubule polymerization is a cellular process typically, though not solely, involved in cell motility and cell division.

    (Microtubule Polymerization Process, NCI Thesaurus)

    A chemical subunit that can undergo polymerization by bonding to other subunits.

    (Monomer, NCI Thesaurus)

    Mitotic kinesins or microtubule-associated proteins (MAPs) are ATP-powered proteins that convert energy into a mechanical force along the microtubule structure following the hydrolysis of ATP, which occurs during microtubule polymerization.

    (Mitotic Kinesin Modulator, NCI Thesaurus)


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