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PPARD wt Allele
Human PPARD wild-type allele is located in the vicinity of 6p21.2 and is approximately 85 kb in length. This allele, which encodes peroxisome proliferator-activated receptor delta protein, plays a role in embryo implantation, placental development, cholesterol homeostasis and transcriptional regulation. (NCI Thesaurus)
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This gene is involved in signaling and transcriptional regulation.
Human PPARA wild-type allele is located within 22q12-q13.1 and is approximately 93 kb in length. This allele, which encodes peroxisome proliferator-activated receptor…
This gene is involved in ligand-mediated transcriptional regulation.
The most recognized mechanism by which peroxisome proliferators regulate gene expression is through a PPAR/RXR heterodimeric complex binding to a peroxisome proliferator-response…
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha,…
Similar to other nuclear hormone receptors, PPAR acts as a ligand activated transcription factor. Upon binding fatty acids or hypolipidemic drugs, PPARa…
