Health / Medical Topics

    PPP2R1B wt Allele

    Human PPP2R1B wild-type allele is located in the vicinity of 11q23.2 and is approximately 40 kb in length. This allele, which encodes serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform protein, plays a role in coordinating the assembly of the protein phosphatase 2A heterodimer. Functional PPP2R1B gene polymorphisms are associated with lung cancer. (NCI Thesaurus)




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