Health / Medical Topics

    Pre-B-Cell Colony-Enhancing Factor

    Pre-B-Cell Colony-Enhancing Factor, encoded by the PBEF gene, is a cytokine that acts on early B-lineage precursor cells by enhancing the effect of IL-7 and SCF on pre-B-cell colony formation. This protein is secreted and expressed in large amounts in bone marrow, liver tissue, and muscle. It is also present in heart, placenta, lung, and kidney tissues. (NCI Thesaurus/LocusLink)




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