Library / English Dictionary

    PREFRONTAL CORTEX

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    The anterior part of the frontal lobeplay

    Synonyms:

    prefrontal cortex; prefrontal lobe

    Classified under:

    Nouns denoting body parts

    Hypernyms ("prefrontal cortex" is a kind of...):

    lobe ((anatomy) a somewhat rounded subdivision of a bodily organ or part)

    Holonyms ("prefrontal cortex" is a part of...):

    cerebral cortex; cerebral mantle; cortex; pallium (the layer of unmyelinated neurons (the grey matter) forming the cortex of the cerebrum)

    Credits

     Context examples: 

    Increasing levels of BDNF in the ventromedial portion of the prefrontal cortex, a brain region involved in compulsive drug and alcohol seeking, returned the mice to moderate levels of alcohol intake.

    (New study identifies gene variant linked to compulsive drinking, NIH)

    In the brain, MRs are mainly located in the amygdala and the prefrontal cortex — two key brain areas involved in the development and maintenance of AUD.

    (NIH findings link aldosterone with alcohol use disorder, National Institutes of Health)

    Already in 2015, the same research group published a meta-study in the journal Intelligence, in which they identified brain regions — among them the prefrontal cortex — activation changes of which are reliably associated with individual differences in intelligence.

    (Smart People Have Better Connected Brains, The Titi Tudorancea Bulletin)

    In the present study, two distinct parts of the medial prefrontal cortex were important for the Uncanny Valley.

    (Scientists identify possible source of the ‘Uncanny Valley’ in the brain, University of Cambridge)

    These findings suggest that seizures may alter how the prefrontal cortex responds to hippocampal activity and thus interfere with normal memory consolidation.

    (Seizures disrupt memory network, NIH)

    The new research shows that OCD is also linked to medial prefrontal cortex abnormality.

    (Deep brain stimulation may significantly improve OCD symptoms, University of Cambridge)

    The researchers found that levels of 103 miRNAs were different in the amygdala and 31 in the prefrontal cortex of mice reared without gut bacteria (GF mice) compared to conventional mice.

    (New Light on Link between Gut Bacteria, Anxiety, The Titi Tudorancea Bulletin)

    These scans showed that neural activity patterns in another brain region, the prefrontal cortex, distinguished between categories and that subjects used that information to make their judgments.

    (How does the brain learn categorization for sounds? The same way it does for images, National Science Foundation)

    The prefrontal cortex area of the brain oversees important functions such as judgment, decision making, and problem solving, as well as emotional control and memory.

    (How the brain pays attention to faces and places, NIH)

    This pattern involved what scientists described as neuroflexibility, in a circuit between the brain’s medial prefrontal cortex and forebrain regions including the ventral striatum, extended amygdala, and hippocampus during sustained stress exposure.

    (Researchers identify brain circuits that help people cope with stress, NIH)


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