PRF1 wt Allele

Human PRF1 wild-type allele is located in the vicinity of 10q22 and is approximately 5 kb in length. This allele, which encodes perforin-1 protein, plays a role in lymphocyte-mediated cytolysis. Mutation of the gene is associated with T-cell lymphoblastic lymphoma, aplastic anemia, hemophagocytic lymphohistiocytosis familial type 2, autoimmune lymphoproliferative syndrome and other lymphoproliferative disorders, including various forms of lymphoma. (NCI Thesaurus)

YOU MAY ALSO LIKE

PRF1 Gene

This gene is involved in cytolysis.

PREX2 wt Allele

Human PREX2 wild-type allele is located in the vicinity of 8q13.2 and is approximately 285 kb in length. This allele, which encodes…

PREX2 Gene

This gene is involved in guanine nucleotide exchange.

PREX1 wt Allele

Human PREX1 wild-type allele is located in the vicinity of 20q13.13 and is approximately 204 kb in length. This allele, which encodes…

PREX1 Gene

This gene is involved in signal transduction.

Prevotellaceae

A taxonomic family of bacterium in the phylum Bacteroidetes that includes the genera Hallella, Prevotella and Xylanibacter, among others.