Primary Cutaneous CD4-Positive Small/Medium-Sized T-Cell Lymphoma

A primary cutaneous T-cell lymphoma. It usually presents with a solitary plaque or tumor on the face, neck, or upper trunk. Morphologically, it is composed of small to medium-sized CD4-positive, CD8-negative, and CD30-negative pleomorphic T-lymphocytes. A small number of large pleomorphic T-lymphocytes may also be present. The lymphocytic infiltrate is dermal. Focal epidermotropism and subcutaneous involvement may be present. The prognosis is favorable. (NCI Thesaurus)

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