Health / Medical Topics

    Prion Pathway

    Transmissible spongiform encephalopathy (TSE) is thought to result from the structural conversion of cellular prion protein, PrP(C), into a misfolded oligomeric form, PrP(Sc). PrP is a cell membrane GPI anchored glycoprotein that is expressed in most tissues and in high levels in the nervous system. Some likely cellular functions of PrP are (1) cell protection against oxidative stress, (2) induction of neuronal cell adhesion, neurite extension and maintenance, and (3) neuroprotective signaling through a cAMP/PKA-dependent pathway. (NCI Thesaurus/BIOCARTA)




    YOU MAY ALSO LIKE

    Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of…
    An inactive ingredient of the solid pharmaceutical dosage form added to cement the active and inert components of tablets together to maintain…
    A unit of length equal to 0.013837 inch or 0.35145 millimeter.
    An electronic device that is designed to transfer text or images to paper or other substrate.
    An item in printed form that cannot be classified within a particular set of terms.
    A circuit board that has connections that are preapplied, usually added using photo-resist and acid etching techniques.

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact