| Health / Medical Topics |
Progesterone Vaginal Insert
A tablet preparation formulated for vaginal administration containing a micronized synthetic form of the endogenous steroid hormone progesterone with progesterone activity. Upon vaginal insertion, progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogen by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy. (NCI Thesaurus)
YOU MAY ALSO LIKE
Progesterone Secretion consists of the activities involved in release into the bloodstream by the corpus luteum and placenta of a steroid estrogen…
Progesterone Secretion Inhibition consists of interference with, or restraint of, activities involved in release into the bloodstream by the corpus luteum and…
A lab test to find out if cancer cells have progesterone receptors (proteins to which the hormone progesterone will bind). If the…
Indicates the progesterone receptor level measured in a primary tumor or in metastases. (>=10 is positive if measured in fmols/mg cytosol protein;…
Describes cells that have a protein to which the hormone progesterone will bind. Cancer cells that are progesterone receptor positive need progesterone…
Describes cells that do not have a protein to which the hormone progesterone will bind. Cancer cells that are progesterone receptor negative…
