Health / Medical Topics

    PSEN2 wt Allele

    Human PSEN2 wild-type allele is located within 1q31-q42 and is approximately 26 kb in length. This allele, which encodes presenilin-2 protein, plays a role in the modulation of proteolysis. Mutation of the gene is associated with Alzheimer disease. (NCI Thesaurus)




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