PTPN22 wt Allele

Human PTPN22 wild-type allele is located within 1p13.3-p13.1 and is approximately 123 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 22 protein, plays a role in the dephosphorylation of protein-tyrosine phosphates. Functional PTPN22 gene polymorphisms are associated with susceptibility to insulin-dependent diabetes mellitus, rheumatoid arthritis, systemic lupus erythematosus, and Hashimoto thyroiditis. (NCI Thesaurus)

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PTPN22 Gene

This gene plays a role in the regulation of the immune system, the development of autoimmunity and the cellular response to…

PTPN13 wt Allele

Human PTPN13 wild-type allele is located in the vicinity of 4q21.3 and is approximately 221 kb in length. This allele, which encodes…

PTPN13 Gene

This gene is involved in both protein dephosphorylation and signal transduction.

PTPN12 wt Allele

Human PTPN12 wild-type allele is located in the vicinity of 7q11.23 and is approximately 103 kb in length. This allele, which encodes…

PTPN12 Gene

This gene plays a role in the regulation of cell shape and mobility.

PTPN11 wt Allele

Human PTPN11 wild-type allele is located within 12q24 and is approximately 91 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…