Health / Medical Topics

    Pyrazoloacridine

    Pronunciation

    Definition 1

    A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called acridines. (NCI Dictionary)

    Definition 2

    A 9-methoxy acridine compound containing a reducible 5-nitro substituent. Pyrazoloacridine appears to intercalate into DNA and inhibit RNA synthesis, DNA synthesis, and the activities of topoisomerases I and II, thereby causing cytotoxicity. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A class of heterocyclic organic compounds characterized by a ring structure composed of three carbon atoms and two nitrogen atoms in adjacent…
    A heterocyclic organic compound characterized by a ring structure composed of three carbon atoms and two nitrogen atoms in adjacent positions, with…
    A nucleoside analog. Pyrazofurin potently inhibits orotidine 5'-monophosphate (OMP) decarboxylase, thereby interfering with de novo synthesis of uridine nucleotides and resulting…
    A substance that is being studied in the treatment of cancer.
    A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs)…
    A hydrocarbon-based polymer containing a pyran nucleus used to bioconjugate various drugs,. Use of a pyran polymer-drug bioconjugate may alter the biodistribution…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact