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Pyroxamide
Pronunciation
Definition 1
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called histone deacetylase inhibitors. (NCI Dictionary)
Definition 2
A synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. (NCI Thesaurus)
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