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RADIOISOTOPE
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I. (noun)
Sense 1
Meaning:
A radioactive isotope of an element; produced either naturally or artificially
Classified under:
Hypernyms ("radioisotope" is a kind of...):
isotope (one of two or more atoms with the same atomic number but with different numbers of neutrons)
Hyponyms (each of the following is a kind of "radioisotope"):
tracer ((radiology) any radioactive isotope introduced into the body to study metabolism or other biological processes)
label (a radioactive isotope that is used in a compound in order to trace the mechanism of a chemical reaction)
iodine-131 (heavy radioactive isotope of iodine with a half-life of 8 days; used in a sodium salt to diagnose thyroid disease and to treat goiter)
iodine-125 (light radioactive isotope of iodine with a half-life of 60 days; used as a tracer in thyroid studies and as a treatment for hyperthyroidism)
Context examples:
A radiopharmaceutical composed of the nonspecific perfusion agent ethylglyoxal bis(thiosemicarbazone) (ETS) linked to the beta-emitting, radioisotope copper Cu 62, with potential tumor imaging activity upon positron emitting tomography (PET).
(Copper Cu 62 Ethylglyoxal Bis(thiosemicarbazone), NCI Thesaurus)
A radioimmunoconjugate consisting of the humanized monoclonal antibody lintuzumab conjugated to the alpha-emitting radioisotope actinium Ac 225 with potential antineoplastic activity.
(Actinium Ac 225 Lintuzumab, NCI Thesaurus)
A diagnostic radioimmunoconjugate comprised of the recombinant humanized monoclonal antibody trastuzumab conjugated with the positron-emitting radioisotope copper Cu 64.
(Copper Cu 64 Trastuzumab, NCI Thesaurus)
A uniform distribution of a radioisotope in a large container which can be placed in an imaging device for purposes of quality control checking.
(Flood Source, NCI Thesaurus)
Upon binding, the radioisotope moiety may be detected using PET, thereby allowing the imaging and quantification of CD20-expressing tumor cells.
(Copper Cu 64-DOTA-Rituximab, NCI Thesaurus)
This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes such as technetium 99m, in bone imaging.
(Medronic Acid, NCI Thesaurus)
When conjugated with a radioactive isotope, Lym-1 monoclonal antibody selectively transports the cytotoxic radioisotope to HLA-Dr10-expressing tumor cells, thereby sparing healthy B-cells and normal tissues.
(Monoclonal Antibody Lym-1, NCI Thesaurus)
This agent is reacted in the nuclear pharmacy with Indium-111 radioisotope to form the active radioimmune conjugate, which is injected for radioimaging of tumors expressing TAG-72.
(Chelate-Monoclonal Antibody B72.3, NCI Thesaurus)
A radioconjugate containing the acetate salt of eribulin, labeled with the beta particle-emitting radioisotope carbon C 14, with radioisotopic and potential antineoplastic activities.
(Carbon C 14 Eribulin Acetate, NCI Thesaurus)
Upon imaging of the radioisotope, the distribution patterns and metabolism of phytofluene can be further elucidated which may aid in the understanding of the bioactivity of this agent.
(Carbon C 13 Phytofluene, NCI Thesaurus)
